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- Unit Price：
- Quantity：
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Code：707249-001
- Prograf Granules 0.2mg : 50 bags
- $280.49
Up to 1 pieces per person
10% discount for total amount over $100
shipping schedule : 5 to 10 working days after payment.
warehouse：Japan1
Manufacturer ：Astellas Pharma
Brand ：Astellas Pharma
JAN Code：4987233198932
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Description
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This medicine acts on immune-related T cells and suppresses inflammation by inhibiting the production of cytokines associated with inflammation. It will improve symptoms of refractory ulcerative colitis.
It is usually used to treat ulcerative colitis.
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Presentation
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50 bags
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Feature
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white granule
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Active Ingredients
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Tacrolimus hydrate
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Effect/Efficacy
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This medicine acts on immune-related T cells and suppresses inflammation by inhibiting the production of cytokines associated with inflammation. It will improve symptoms of refractory ulcerative colitis.
It is usually used to treat ulcerative colitis.
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Usage/Dosage
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In general, for adults, take initially 0.025 mg/kg of tacrolimus at a time twice daily after meal in the morning/evening. For subsequent 2 weeks, the dosage may be adjusted according to the patient's blood concentration. The maximum daily dose is 0.3mg/kg in principle.
One capsule of this preparation contains 5 mg of tacrolimus. Strictly follow the instructions.
If you miss a dose, take a dose as soon as possible. However, the next dose should be at least 5 hours apart. You should never take two doses at one time or change the dosing schedule.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
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Cautions
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If you have previously experienced any allergic reactions (itch, rash etc.) to any medicines.
If you have hepatic disorder, renal disorder, or infections.
If you are pregnant, possibly pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Since you are likely to become infected, wash hands and gargle and regulate your daily life.
Grapefruit (juice) may enhance this medicine's effect, resulting in renal disorder. Avoid intake of grapefruit (juice) together with the medicine.
Foods/drinks containing Hypericum perforatum (St. John's wort) may reduce this medicine's effect. Avoid intake of these foods/drinks together with the medicine.
Keep out of the reach of infants and children. Store away from direct sunlight, heat and moisture.
Discard the remainder. Do not store them. Ask the pharmacist or medical facility how to discard them.
Do not receive vaccination without an approval of your doctor.
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Contraindication
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The most commonly reported adverse reactions include tremor (tremble of hands/feet), hot flush, paraesthesia, nausea, renal dysfunction, hepatic dysfunction and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, see your doctor immediately.
decrease in urinary output, general edema, thirst [acute renal disorder, nephrotic syndrome]
palpitations, shortness of breath, chest distress, general edema, chest pain [heart failure, arrhythmia, myocardial infarction, angina pectoris, pericardial effusion, myocardial disorder]
convulsion, consciousness disorder, language disorder [central nervous system disorders including reversible posterior leukoencephalopathy syndrome, hypertensive encephalopathy, progressive multifocal leukoencephalopathy]
headache, temporary conscious disorder, paralyzation on either side of the body [cerebrovascular disorder]
respiratory distress, breathing difficulty [respiratory distress]
fever, general malaise, cold-like symptoms [infections]
dry mouth, excessive drinking/urination, getting tired easily [diabetes mellitus, hyperglycemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
