- ：
- Unit Price：
- Quantity：
Original
-
Code：009025-002
Original
- Rheumatrex Capsules 2mg : 30 capsules
- $220.99
Sales have been closed.
10% discount for total amount over $100
warehouse：Japan1
Manufacturer ：Pfizer
Brand ：Pfizer
JAN Code：4987114537409
-
Description
-
This medicine suppresses actions of lymphocytes in the immune system or of cells which relates to inflammation. It inhibits abnormal immune reaction to improve articular symptoms such as swelling and pain.
It is usually used to treat rheumatoid arthritis and juvenile idiopathic arthritis with arthral symptom.
-
Presentation
-
30 capsules
-
Feature
-
yellow/yellow capsule, major axis: 14.7 mm, minor axis: 5.3 mm
-
Active Ingredients
-
Methotrexate 2mg
-
Effect/Efficacy
-
This medicine suppresses actions of lymphocytes in the immune system or of cells which relates to inflammation. It inhibits abnormal immune reaction to improve articular symptoms such as swelling and pain.
It is usually used to treat rheumatoid arthritis and juvenile idiopathic arthritis with arthral symptom.
-
Usage/Dosage
-
For rheumatoid arthritis: In general, take this medicine as a unit of one week (7 days). Weekly total dosage is 3 capsules (6 mg of the active ingredient), taken at once or in 2 to 3 divided doses. When dividing the dosage, take the dosage every 12 hours from day 1 to day 2. The remaining 6 days (when the dosage is taken at once or divided in two doses) or 5 days (when the dosage is divided in three doses) will be a non-medication day. This course is repeated every week. The dosage may be adjusted according to the age, symptoms, tolerance and response to this medicine. However, the weekly dosage is up to 8 capsules (16 mg).
For juvenile idiopathic arthritis with arthral symptom: In general, take this medicine as a unit of one week (7 days). Weekly total dosage is 4 to 10 mg of the active ingredient per square meter (/m2), taken at once or in 2 to 3 divided doses. When dividing the dosage, take the dosage every 12 hours from day 1 to day 2. The remaining 6 days (when the dosage is taken at once or divided in two doses) or 5 days (when the dosage is divided in three doses) will be a non-medication day. This course is repeated every week. The dosage may be adjusted according to the age, symptoms, tolerance and response to this medicine. This preparation contains 2 mg of the active ingredient in a capsule.
In any case, strictly follow the instructions.
Take the medicine with a large amount of water and avoid taking right before bedtime. (Esophageal retention of this medicine for a long time may cause ulcer. )
If you miss a dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
-
Cautions
-
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have: myelosuppression, chronic liver disorder, renal disorder, pleural effusion, ascites, tuberculosis, affected by tuberculosis or close contact with tuberculosis patient.
If you are pregnant, possibly pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Since clinical case with possibility of teratogenicity has been reported, pay attention so that you or your partner dose not become pregnant during taking the medicine.
Keep out of reach of children. Store away from direct sunlight, heat and moisture.
Discard the remainder. Do not store them. If you dispose of unused medicines, seek advice of your pharmacist or healthcare provider about proper disposal of them.
Do not receive live vaccines (rubella, mumps, chickenpox, and measles vaccine, oral polio virus vaccine, BCG, etc. ), because use of live vaccines may intensify and continue the vaccine-derived infection during taking this medicine.
-
Contraindication
-
The most commonly reported adverse reactions include liver dysfunction, stomatitis, malaise, nausea, rash, itch, fever, hives and photosensitivity. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
cold feeling, respiratory distress, dropping blood pressure [shock, anaphylaxis]
fever, sore throat, cold-like symptoms [myelosuppression]
loss of appetite, general malaise, yellowing of the skin and the white of eyes [fulminant hepatitis, liver failure]
decreased urine output, edema of face, etc., dry mouth [acute renal disorder, tubulonecrosis, severe nephropathy]
fever, cough (dry cough), respiratory distress [interstitial pneumonia, pulmonary fibrosis, pleural effusion]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
